Type of Document	Dissertation
Author	Tladi, Dawn Mahube
Author's Email Address	dtladi@yahoo.com
URN	etd-04102006-183816
Title	Effects of Acute Exercise on Plasma Lipids and Lipoproteins of Obese Women
Degree	Doctor of Philosophy
Department	Nutrition, Food, and Exercise Science, Department of
Advisory Committee	Advisor Name Title R. J. Moffatt Committee Chair D. Quadagno Committee Member L. B. Panton Committee Member
Keywords	Plasma Lipids And Lipoproteins Women Exercise Obesity
Date of Defense	2006-03-13
Availability	unrestricted
Abstract EFFECTS OF ACUTE EXERCISE ON PLASMA LIPIDS AND LIPOPROTEINS OF OBESE WOMEN Name: Dawn Tladi Department: Nutrition, Food and Exercise Sciences Major Professor: Dr R. J. Moffatt Degree: Doctor of Philosophy Term Degree Awarded: Spring, 2006 Acute exercise reduces triglycerides (TG) and increases high-density lipoprotein cholesterol (HDL-C) and HDL2-C in both men and women. However, data are sparse in obese women, who might benefit more from the effects of exercise, since they are more likely to have higher TG and lower HDL-C. PURPOSE: To investigate the acute effects of moderate intensity walking on plasma lipids and lipoproteins of obese Black and White women. METHODS: Twenty-four premenopausal and eumenorrheic sedentary obese White (n=9) and Black (n=15) women (Means ± SD; age = 24.5 ± 4.8 yrs; BMI = 33.5 ± 3.7 kg/m2; body fat = 48.3 ± 5.3%) walked on a treadmill at 70 ± 5% VO2peak to expend 300 and 500 kcal. Fasted blood samples were collected before (baseline), immediately post, 24, and 48hrs after exercise and were analyzed for total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), TG, HDL-C, HDL2-C, and HDL3-C. RESULTS: No significant differences were found in all analyzed parameters between races and sessions over time, except for TG. During the 300 kcal session TG had a non-significant increase from baseline to immediately post and then a 20.1% (p < 0.05) decrease at 48hrs after exercise (Baseline: 57.3 ± 16.4; immediately post: 69.0 ± 18.6; 24hrs: 55.8 ± 20.2; 48hrs: 55.1 ± 19.3 mg·dL-1). During the 500 kcal session TG increased by 30.1% from baseline to immediately post and then decreased by approximately 36% from immediately post at 24 and 48hrs after exercise (Baseline: 60.5 ± 24.6; immediately post: 86.8 ± 39.8; 24hrs: 55.2 ± 20.2; 48hrs: 55.0 ± 19.3 mg·dL-1). CONCLUSION: Obese women responded with increased TG immediately post exercise before returning to baseline values at 24 hrs after exercise, as opposed to the decrease usually observed immediately post exercise in non-obese women. Plasma HDL-C and HDL2-C of obese women seem to be resistant to the increase usually observed with acute exercise in non-obese women. The different response by obese women may be due to the effect obesity has on plasma lipid and lipoprotein metabolism.
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