Platelet monoamine oxidase (MAO) activity levels have been connected to a wide variety of antisocial behavioral outcomes. Most notably, platelet MAO has been associated with alcohol dependence, aggression, impulsive/risky behavior, and psychopathy.
However, no one has sought to synthesize the extant literature to ascertain the current standing of the relationship. These analyses seek to address this deficit within the literature by examining the relationship between platelet MAO and the aforementioned antisocial outcomes. By estimating these subsets within the published literature an overall view of the relationship, as it currently stands, is formed.
It was initially hypothesize that low platelet MAO activity levels would consistently predict antisocial behaviors. However, one empirically examined, and while accounting for possible unpublished studies, the relationship appears less predictive and stable then initially believed. The results of these analyses are preliminary and further research should be conducted to determine the true nature of the relationship.
